IZN Seminar:


24.10.2014 15:00

BCCN Seminar:

NMDA Receptor Hypofunction Leads to Generalized and Persistent gamma Frequency (30-80 Hz) Oscillations: Signal and Noise in Corticothalamic Systems

Prof. Didier Pinault
INSERM, Université de Strasbourg, Faculté de médecine Strasbourg, France

N-methyl D-aspartate type glutamate receptor antagonists induce schizophreniform disorder symptoms accompanied with deficits in sensory-perception and cognition and with a persistent amplification of electroencephalographic baseline gamma frequency (30-80 Hz) oscillations in cortical and subcortical regions, including the thalamus. This generalized network gamma noise might be the source of abnormal activities (e.g, during hallucinations) and disturb function-related synchronized oscillations. The corresponding gamma signal-to-noise ratio is proposed as a potential electrophysiological biomarker of network dysfunctions responsible for disturbances in sensorimotor and cognitive information processing associated with mental disorders. Testing theoretical and pathophysiological hypotheses is an appealing and promising basic-clinical translational way to understand how, in health and disease, our brain at work combines its various and miscellaneous molecular, synaptic, cellular and architectural complexities.

SR14, Im Neuenheimer Feld 306


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Kuner T Fig1
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Professor Herta Flor erhält Ehrung für ihr wissenschaftliches Lebenswerk

flor.jpgProfessor Herta Flor, Wissenschaftliche Direktorin des Instituts für Neuropsychologie und Klinische Psychologie am ZI, wurde am 22. September 2014 von der Deutschen Gesellschaft für Psychologie (DGPs) für ihr wissenschaftliches Lebenswerk geehrt. Den Preis nahm die Schmerzforscherin, die in den Bereichen der Klinischen Psychologie, der Psychotherapie und der Neuropsychologie zu den bedeutendsten internationalen Wissenschaftlerinnen zählt, im Rahmen des 49. DGPs-Kongresses in Bochum entgegen. Externer Inhalt

New findings on the link between nerve cells at the interface to the hippocampus

EngelhardtA team led by Dr Jakob von Engelhardt focused on the ‘AMPA’ receptors. These bind the neurotransmitter ‘glutamate’ and are particularly common in the brain. “We looked at AMPA receptors in an area of the brain, which constitutes the main entrance to the hippocampus,” explains von Engelhardt, who works for the DZNE and DKFZ. “The hippocampus is responsible for learning and memory formation. Among other things it processes and combines sensory perception. We therefore asked ourselves how the flow of information into the hippocampus is controlled.” Externer Inhalt

German National Brain Bee was record breaking in 2014

The three Heidelberg University neuroscientists who served as judges were Prof. Dr. Armin Blesch, Director of the Laboratory for Neuroregeneration at the Spinal Cord Injury Center, Prof. Dr. Stephan Frings, Coordinator of the Interdisciplinary Neurosciences Centre Masters Program, and Dr. Lucia Poggi of the Neurodevelopment Division of the Centre for Organismal Studies. Externer Inhalt


Open positions at the IZN

  • The Carl group is seeking a highly motivated PhD student holding a masters/diploma degree in natural sciences. Experience in the fields of developmental and/or neurobiology as well as zebrafish and/or confocal imaging is preferred. Adobe

  • The Pollerberg group is offering a PhD position in a project studying the role of cell adhesion molecules (CAMs) and their interaction partners for axon growth and regeneration. Adobe

  • The Pollerberg group is offering a PhD position in a project studying the role of microtubules and microtubule-associated proteins for axon growth and navigation. Adobe


Managing Director:
Prof. Dr. Hilmar Bading
Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8218
Fax:  +49 - 6221 - 54 6700
eMail:  Hilmar.Bading@uni-hd.de


Dr. Otto Bräunling
Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8694, 56 39007
Fax:  +49 - 6221 - 54 6700
eMail:  Braeunling@uni-hd.de


Administration & Information:
Dipl.-Biol. Ute Volbehr
IZN, University of Heidelberg
Im Neuenheimer Feld 326, 3.OG
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 6498 mornings
  +49 - 6221 - 54 8227 afternoons
Fax:  +49 - 6221 - 54 4561
eMail:  izn@uni-hd.de
Editor: Webmaster
Latest Revision: 2014-10-22
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