Upcoming IZN Events:

10.02.2016      13:00

Neurobiology Lecture:


Taking a deeper look into the genetic and epigenetic basis of learning

Stefan Bonn
DZNE, Göttingen


HS2, Im Neuenheimer Feld 306, Heidelberg

12.02.2016      15:00

BCCN Seminar:


Translational Neuromodeling

Prof. Klaas Enno Stephan
University of Zurich & ETH Zurich, Switzerland

For many brain diseases, particularly in psychiatry, we lack objective diagnostic tests and cannot predict optimal treatment for individual patients. This presentation outlines a translational neuromodeling framework which aims at establishing “computational assays” for inferring subject-specific mechanisms of brain disease from non-invasive measures of behaviour and neuronal activity. Such assays, derived from a generative modelling approach, may provide a formal basis for differential diagnosis and treatment predictions in individual patients and, eventually, facilitate the construction of pathophysiologically grounded disease classifications. The framework presented emphasises the importance of prospective validation studies in patients and of concrete clinical problems for providing benchmarks for model validation. I will show some early (and mostly very simple) proof of concept studies in patients, and outline the opportunities and challenges that lie ahead.


Zentralinstitut für Seelische Gesundheit, J 5, Mannheim

10. & 11.07.2016

​IZN RetreatKloster Schoental

Kloster Schöntal

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Chica and Heinz Schaller Foundation Honours Outstanding Young IZN/DKFZ Scientist

Dr. Hai-Kun Liu
Hai-Kun Liu is investigating how stem cells develop in the adult brain, with the goal of understanding how tumours develop. His work on the relationship between brain stem cells and brain tumour stem cells has yielded important results. He identified the Tlx protein as the key molecule in brain tumour stem cells. When the Tlx molecule was genetically switched off in mice, the tumour stem cells were unable to regenerate and the diseased animals survived longer. Tlx therefore holds much promise for new treatment strategies for glioblastoma, the most aggressive type of brain tumour. Liu and his associates also succeeded in tracking the genetic lineage of brain tumour stem cells in the living organism.   Externer Inhalt


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IZN/Chica and Heinz Schaller Young Investigator Neuroscience Award

Call for Nominations for the 2016 Award

The IZN/Chica and Heinz Schaller Young Investigator Neuroscience Award is an annual prize offered by the Chica and Heinz Schaller Foundation and is given in recognition of an outstanding first-author research publication in any aspect of neuroscience. Candidates must be current members of IZN research groups or have been members while the relevant work was performed. IZN group leaders are excluded unless the work was clearly done during their post-doctoral or PhD period at IZN. Self‐nomination of candidates is encouraged. Deadline for nominations is May 30, 2016 and the award winner will be notified at the end of June 2016. The prize money of 1,000 € is to be used at the winner’s or winners’ discretion and may be divided between equally contributing first authors. The prize will be presented at an award ceremony during the annual IZN retreat, July 10-11, 2016 at Kloster Schöntal, where the successful candidate will give a 10-minute presentation of his/her work.

Applications should include:

  • CV
  • Scientific justification (one page, single spaced, Arial 11)
  • Summary of the significance of the work in lay terms (half a page, single spaced, Arial 11)
  • Original paper published or accepted for publication in 2015 or before May 30, 2016.

Please send your application by email or dropbox to Prof.Dr. Ricarda Diem E-Mail on behalf of the IZN award selection committee. Adobe  Chica and Heinz Schaller Foundation


Johann Peter Süßmilch-Medaille 2015 an Dr. Klaus H. Maier-Hein

Dr. Klaus H. Maier-Hein
Die Johann Peter Süßmilch-Medaille 2015 wurde an Dr. Klaus H. Maier-Hein für die Arbeit "Widespread white matter degeneration preceding the onset of dementia" verliehen.

Der Preis wird zur Förderung des wissenschaftlichen Nachwuchses für hervorragende Arbeiten in den Fachgebieten der GMDS ausgeschrieben und ist mit einem Preisgeld in Höhe von 2.500 Euro dotiert.  Externer Inhalt


Research findings of Heidelberg neurobiologists could lead to new treatment approaches for memory loss and anxiety disorders

Prof. Hilmar Bading
Increasing the level of a certain DNA-modified enzyme in the brain significantly improves cognitive ability. The discovery was made by the research team led by Prof. Dr. Hilmar Bading at the Interdisciplinary Center for Neurosciences of Heidelberg University. Mouse experiments showed that the Dnmt3a2 protein can boost memory performance in the animals. Because this protein also affects fear memory and the ability to erase bad memories, the researchers hope these findings can be used to develop new treatments for post-traumatic stress disorder and other forms of anxiety. The results of the research were published in the journal Molecular Psychiatry.

In an earlier study, the Heidelberg scientists learned that there are reduced levels of Dnmt3a2 protein in the brains of older mice. When the elderly animals were injected with viruses that produce this protein, their memory capacity improved. “Now we have found that increasing the Dnmt3a2 level in the brains of younger mice also boosts their cognitive ability”, explains Prof. Bading. In a number of different long-term memory tests, including classic Pavlovian conditioning, the scientists were able to demonstrate that mice with more Dnmt3a2 on board performed considerably better.  Externer Inhalt


Open positions at the IZN

  • The lab of Christoph Körber at the Department of Functional Neuroanatomy (Prof. Thomas Kuner), Institute of Anatomy and Cell Biology, Heidelberg University is looking for a PhD student working on the role of K2P channels in auditory brainstem function.  Adobe  posted 11.2015
  • The Nordström group in the Department of Cellular and Molecular Pathology, DKFZ Heidelberg is seeking an exceptionally motivated and skilled PhD student in Neurobiology for the study of "Gangliosides in Body Weight Regulation and Neuronal Stem Cells".  Adobe posted 11.2015
  • The Cambridge group (Kuner department) is offering a PhD position to work on 'In vivo two-photon microscopy and optogenetic tools'  Adobe  posted 09.2015


Managing Director:
Prof. Dr. Hilmar Bading
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8218
Fax:  +49 - 6221 - 54 6700
email:  Bading@nbio.uni-heidelberg.de


Dr. Otto Bräunling
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364, 1.OG
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8694, 56 39007
Fax:  +49 - 6221 - 54 6700
email:  Braeunling@nbio.uni-heidelberg.de


Administration & Information:
Irmela Meng
IZN-Neurobiology, University of Heidelberg
Im Neuenheimer Feld 364, 1.OG
D-69120 Heidelberg, Germany

Phone:  +49 - 6221 - 54 8219
Fax:  +49 - 6221 - 54 6700
email:  Sekretariat@nbio.uni-heidelberg.de


Editor: Webmaster
Latest Revision: 2016-02-05
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